guidance AI Agent Skills

Guidance

21.8k

davila7

Control LLM output with regex and grammars, guarantee valid JSON/XML/code generation, enforce structured formats, and build multi-step workflows with Guidance - Microsoft Research's constrained generation framework

protein-design-workflow

100

adaptyvbio

End-to-end guidance for protein design pipelines. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Planning compute resources and timelines, (5) Integrating multiple design tools. For tool selection, use binder-design. For QC thresholds, use protein-qc.

binder-design

100

adaptyvbio

Guidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).

dag-feedback-synthesizer

43

curiositech

Synthesizes actionable feedback from validation results, confidence scores, and iteration triggers. Creates structured improvement guidance for re-execution. Activate on 'synthesize feedback', 'improvement suggestions', 'actionable feedback', 'iteration guidance', 'feedback generation'. NOT for iteration detection (use dag-iteration-detector) or convergence tracking (use dag-convergence-monitor).